Ingénieur de recherche clinique

En poste depuis 16 ans en qualité d’ingénieur en recherche clinique pédiatrique au CHU Clermont Ferrand. J’ai travaillé sur divers projets de recherche clinique pédiatrique portant sur des pathologies telles que les leucémies et cancers solides, l’obésité, le diabète de type 1 et la rhumatologie. J’ai soutenue en 2018 une thèse d’Université sur les adaptations cellulaires et moléculaires de la réponse inflammatoire à l’activité physique chez les enfants et adolescents atteints de pathologies auto-immunes. Rattachée au laboratoire, j’ai développé en collaboration avec le Pr Pascale Duché un projet de recherche clinique sur l’évaluation de l’impact des pathologies chroniques et de leur traitement sur la condition physique des enfants et adolescents.
Pour me contacter :
Centre de Recherche Clinique chez l’Enfant – Antenne pédiatrique INSERM CIC1405
Pédiatrie, CHU Estaing, 1 place Lucie et Raymond Aubrac
63003 Clermont Ferrand cedex 1
Tél : 04 73 75 22 97
Courriel : e_rochette@chu-clermontferrand.fr
Principales publications :
- Rochette E, Saidi O, Merlin E, Duché P. Physical activity as a promising alternative for young people with juvenile idiopathic arthritis: Toward an evidence-based prescription. Front Immunol. 2023 Feb 13;14:1119930
- Saidi O, Rochette E, Del Sordo G, Peyrel P, Salle J, Doré E, Merlin E, Walrand S, Duché P. Isocaloric diets with different protein-carbohydrate ratios: the effect on sleep, melatonin secretion and subsequent nutritional response in healthy young men. Nutrients. 2022 Dec 13;14(24):529. PMID: 36558458
- Paysal J, Thireau J, Terral D, Rochette E, Obert P, Merlin E, Nottin S. Cardiac remodeling and its determinants in anorexia nervosa adolescent: impact of weight recovery. Children. 2022 Mar 24;9(4):458. PMID: 35455501
- Paysal J, Merlin E, Terral D, Chalard A, Rochette E, Obert P, Nottin S. Left ventricular strains and myocardial work in adolescents with anorexia nervosa. Front Cardiovasc Med. 2022 Feb 8;9:798774. PMID: 35211523
- Saidi O, Rochette E, Del Sardo G, Doré E, Merlin E, Walrand S, Duché P. Eucaloric balanced diet improve objective sleep in adolescents with obesity but not normal weight controls compared to ad libitum feeding. Nutrients. 2021 Oct 10;13(10):3550. PMID: 34684551
- Paysal J, Merlin E, Rochette E, Terral D, Nottin S. Global and regional myocardial work in female adolescents with weight disorders. J Clin Med. 2021 Oct 12;10(20):4671. PMID: 34682793
- Saidi O, Rochette E, Bourdier P, Ratel S, Merlin E, Pereira B, Duché P. Sleep in youth juvenile idiopathic arthritis and inflammatory bowel diseases: A systematic review, meta-analysis and methodologic considerations for advancing the field. Sleep. 2021 Sep 15:zsab233. PMID: 34525202
- Fel S, Rochette E, Walther G, Pereira B, Merlin E, Terral D, Duché P. Maximal Fat Oxidation During Exercise Is Already Impaired in Pre-pubescent Children With Type 1 Diabetes Mellitus. Front Physiol. 2021 Apr 9;12:664211. PMID: 33897473
- Saidi O, Pereira B, Peyrel P, Maso F, Doré E, Rochette E, Ratel S, Walrand S, Duché P. Sleep pattern in elite adolescent rugby players during two weeks of the in-season competitive phase: that big sporting weekend while being sleepy! European Journal of Sport Science, 2021 Feb. PMID: 33546579
- Bourdier P, Birat A, Rochette E, Doré E, Pereira B, Merlin E, Ratel S, Duché P. Muscle function and architecture in children with juvenile idiopathic arthritis. Acta Paediatrica. 2021 Jan;110(1):280-287. PMID: 32420673
- Saidi O, Rochette E, Doré E, Fantini L, Merlin E, Pereira B, Walrand S, Duché P. Effect of proteins supplementation with different Trp/Lnaa ratio on sleep in young elite athletes: A double-blind controlled trial (PROTMORPHEUS). Nutrients 2020, 12, 1885. PMID: 32599773
- Grand A, Rochette E, Dutheil F, Gozal D, Calcaterra V, Canani B, Cobanoglu N, Derikx J, Terrin G, Pereira B, Merlin E. Body mass index and blood calprotectin level correlation in healthy children: An individual patient data meta-analysis. J Clin Med. 2020 Mar 20;9(3): 857. PMID: 32245056
- Pegon C, Rochette E, Pereira B, Doré E, Isfan F, Grèze V, Merlin E, Kanold J, Duché P. Childhood leukemia survivors and metabolic response to exercise: a pilot-controlled study. J. Clin. Med. 2020;9(2): 562. PMID: 32092881
- Saidi O, Rochette E, Bovet M, Merlin E, Duché P. Acute moderately-intense exercise improves sleep and decreases next morning consumption of energy-dense food in adolescent obese girls. Pediatr Obes. 2020;e12613. PMID:32020733
- Papalia H, Rochette E, Pereira B, Merlin E, Kanold J, Duché P. Metabolic response to exercise in childhood brain tumor survivors: A pilot controlled study. Pediatr Blood Cancer. 2020;67(2):e28053. PMID: 31625676
- Rochette E, Bourdier P, Pereira B, Doré E, Birat A, Ratel S, Echaubard S, Duché P, Merlin E. TNF-α blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2019 Jul 22;17(1):47. PMID: 31331342
- Rochette E, Pereira B, Merlin E. Questions regarding the relationship between serum levels of S100A8/A9 and S100A12 and the maintenance of clinically inactive disease in JIA: comment on the article by Claas H. Hinze et al. Arthritis Rheumatol. 2019 Jun 24. PMID: 31233280
- Rochette E, Bourdier P, Pereira B, Echaubard S, Borderon C, Caron N, Chausset A, Courteix D, Fel S, Kanold J, Paysal J, Ratel S, Rouel N, Sarret C, Terral D, Usclade A, Merlin E, Duché P. Impaired muscular fat metabolism in juvenile idiopathic arthritis in inactive disease. Front Physiol. 2019 May 1;10:528. PMID: 31118902
- Bourdier P, Saidi O, Rochette E, Ratel S, Merlin E, Pereira B, Duché P. Physical activity and sedentary levels in children with juvenile idiopathic arthritis and inflammatory bowel disease. A systematic review and meta-analysis. Pediatr Res. 2019 Aug;86(2):149-156. PMID: 31029060
- Rochette E, Duché P, Hourdé C, Evrard B, Pereira B, Echaubard S, Merlin E. Single Bout Exercise in Children with Juvenile Idiopathic Arthritis: Impact on Inflammatory Markers. Mediators Inflamm. 2018 Jun 13;2018:9365745. PMID: 30008613
- Rochette E, Merlin E, Hourdé C, Evrard B, Pereira B, Echaubard S, Duché P. Inflammatory response 24h post-exercise in youth with juvenile idiopathic arthritis. Int J Sports Med. 2018 Aug 17. PMID: 30119133
- Rochette E, Duché P, Merlin E. Juvenile idiopathic arthritis and physical activity: possible inflammatory and immune modulation and tracks for interventions in young populations. Autoimmunity Reviews 14 (2015) 726–734. PMID: 25936296